Program and Schedule 2022

5 October 2022 (Wednesday)

16:00 

Registration opens

17:00

Informal get-together, dinner buffet

19:00 

Conference Opening

19:15

The Murnau Lecture 2022, Chair: Stefan Raunser
Wolfgang Baumeister (MPI Martinsried) – "Structural Biology in situ: the power of seeing the whole picture"

20:15

Beer and snacks

 

6 October 2022 (Thursday)

8:30

Registration open

Session 1

Membrane Transporters | Chair: Oliver Einsle

09:00

Yifan Cheng (University of California San Francisco) – "Single particle cryo-EM of TRPV1: from structural snapshots to gating mechansim"

09:40

Günter Fritz (University of Hohenheim, Stuttgart) – "Cryo-EM and X-ray structures of NADH:quinone oxidoreductase of Vibrio cholerae reveal conformational coupling in redox-driven Na+ translocation"

10:00

Lin Zhang (Albert-Ludwigs-Universität Freiburg) – "Mechanistic insights into the biogenesis and regulation of nitrous oxide reductase"

10:20

Coffee break

10:50

Cristina Paulino (University of Groningen) – "A true chimera: transport mechanism and regulation of the KdpFABC complex"

11:30

Wei Lü (Van Andel Institute Grand Rapids MI) – "Molecular basis for ion channels involved in taste perception"

12:10

Vivien Strauch (Dynamic Biosensors) – "Measurement of small molecule-induced structural changes in RNAs and proteins using switchSENSE®"

12:30

Lunch

Session 2

Molecular Mechanisms | Chair: Michael Hothorn

14:00

Janosch Hennig (University of Bayreuth and EMBL Heidelberg) – "Structural basis of non-coding roX RNA remodelling during dosage compensation"

14:40

Mathias Girbig (EMBL Heidelberg and MPI Marburg) – "Structural analysis of human and yeast RNA polymerase III transcription"

15:00

Klemens Wild (Universität Heidelberg) – "A thermophilic eukaryotic ribosome and its co-translational chaperone"

15:20

Coffee break

15:50

Tanja Mittag (St. Jude Children’s Research Hospital, Memphis TN) – "Interactions mediating phase separation in prion-like low-complexity domains and transformation of condensates into pathogenic fibrils"

16:30

Kulkarni Madhurima (Indian Institute of Science Bangalore) – "An intrinsically disordered protein functions through a conformationally excited state"

16:50

Helmut Grubmüller (MPI Göttingen) – "Three routes to molecular movies"

17:10

Business meeting for GBM members (ca. 50 min),
Poster session

18:15

Dinner buffet

 

7 October 2022 (Friday)

Session 3

Cellular Organization and Signaling | Chair: Irmi Sinning

09:00

Naoko Mizuno (NIH, NHLBI, Bethesda MD) – "Molecular neurobiology by cryo-ET"

09:40

Morris Degen (University of Basel) – "The structural basis for mediated plasma membrane rupture in inflammatory cell death"

10:00

Rhythm Shukla (Utrecht University) – "Two-fold attack of Teixobactin on the bacterial membrane"

10:20

Coffee break

10:50

Gaia Pigino (Human Technopole Milan) – "Structural cell biology of cilia and eukaryotic flagella"

11:30

Xizhou Zhang (MPI Göttingen) – "Transmembrane signaling of sensor kinase CitA"

11:50

Theresia Dunzendorfer-Matt (Medical University of Innsbruck) – "Structural basis of activation of the tumor suppressor protein neurofibromin"

12:10

Free afternoon
13:30

Optional: Guided sightseeing tour

Session 4

Cellular Structural Biology | Chair: Stefan Raunser

16:30

Juli Feigon (UC Los Angeles) – "Structural biology of telomerase mechanism and interactions at telomeres"

17:10

Yanick Fleischmann (ETH Zürich) – "In-cell NMR of the intrinsically disordered protein Prothymosine Alpha reveals its native dynamic histone 1 interaction in cells"

17:30

Dovile Januliene (University of Osnabrück) – "The ABC transporter MsbA adopts the wide inward-open conformation in living cells"

17:50

Coffee break

18:20

Andrea Musacchio (MPI Dortmund) – "Chromosome segregation: intrinsically divisive"

19:00

Dmitry Shvarev (University of Osnabrück) – "Structure of the lysosomal membrane fusion machinery"

19:20

Gavin Rice (MPI Dortmund) – "TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining"

19:40

Walk to Brauhaus Griesbräu

20:15

Conference dinner at Brauhaus Griesbräu, Murnau

 

8 October 2022 (Saturday)

Session 5

Biomolecular Dynamics | Chair: Sebastian Hiller

09:00

Hashim Al-Hashimi (Columbia University New York) – "The ensemble revolution: quantitative and predictive structural biology"

09:40

Julian Folz (Heinrich-Heine University Düsseldorf) – "FRET measurements resolving structures, dynamics and transitions of various biomolecules"

10:00

Volker Dötsch (University of Frankfurt) – "The molecular switch that guarantees genetic quality in oocytes"

10:40

Coffee break

11:10

Alexander Belyy (MPI Dortmund) – "Actin as the target and activator of bacterial toxins: a structural perspective"

11:30

Carolyn Moores (Birkbeck, University of London) – "Exploring cellular complexity through cytoskeleton regulation"

12:10

End of meeting